Search on: INTERLEUKIN-1 
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Descriptor English:   Interleukin-1 
Descriptor Spanish:   Interleucina-1 
Descriptor Portuguese:   Interleucina-1 
Synonyms English:   Lymphocyte-Activating Factor
IL-1  
Tree Number:   D12.644.276.374.465.501
D12.644.276.374.500.400
D12.776.467.374.465.501
D12.776.467.374.500.400
D23.529.374.465.501
D23.529.374.500.400
Definition English:   A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation. 
Indexing Annotation English:   DF: IL 1 or IL1
See Related English:   Receptors, Interleukin-1
 
History Note English:   1990(1983) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   29487 
Unique Identifier:   D007375 

Occurrence in VHL: 		 

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