Expresión de búsqueda:
WNT PROTEINS
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Wnt Proteins
Descriptor
Español
:
Proteínas Wnt
Descriptor
Portugués
:
Proteínas Wnt
Categoría:
D12.644.276.984
D12.776.467.984
D23.529.984
Definición
Inglés
:
Wnt proteins
are a large
family
of secreted
glycoproteins
that play essential roles in
EMBRYONIC AND FETAL DEVELOPMENT
, and tissue
maintenance
. They bind to
FRIZZLED RECEPTORS
and act as PARACRINE PROTEIN FACTORS to initiate a variety of
SIGNAL TRANSDUCTION
PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator
BETA CATENIN.
Nota Histórica
Inglés
:
2006(1987)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
50759
Identificador Único:
D051153
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS