Expresión de búsqueda: WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY 
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Descriptor Inglés:   Wiskott-Aldrich Syndrome Protein Family 
Descriptor Español:   Familia de Proteínas del Síndrome de Wiskott-Aldrich 
Descriptor Portugués:   Família de Proteínas da Síndrome de Wiskott-Aldrich 
Sinónimos Inglés:   WAS Protein Family
WASP-Family Verprolin Homologous Proteins
WAVE Proteins  
Categoría:   D05.750.078.730.912
D12.776.220.525.912
Definición Inglés:   A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN. 
Nota de Indización Inglés:   WISKOTT-ALDRICH SYNDROME PROTEIN and WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL are also available
Nota Histórica Inglés:   2006(1999) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   50563 
Identificador Único:   D051300 

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