Expresión de búsqueda:
PROTO-ONCOGENE PROTEINS C-BCR
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Proto-Oncogene Proteins c-bcr
Descriptor
Español
:
Proteínas Proto-Oncogénicas c-bcr
Descriptor
Portugués
:
Proteínas Proto-Oncogênicas c-bcr
Sinónimos
Inglés
:
bcr Proto-Oncogene Proteins
c-bcr Proteins
Categoría:
D08.811.913.696.620.682.700.759
D12.776.624.664.700.171
Definición
Inglés
:
Proto-oncogene protein bcr is a serine-threonine kinase that functions as a negative regulator of
CELL PROLIFERATION
and NEOPLASTIC CELL TRANSFORMATION. It is commonly fused with cellular abl protein to form BCR-ABL FUSION
PROTEINS
in
PHILADELPHIA CHROMOSOME
positive
LEUKEMIA
patients.
Nota Histórica
Inglés
:
2006(1988)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
50725
Identificador Único:
D051562
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS