Expresión de búsqueda:
PROTO-ONCOGENE PROTEINS C-AKT
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DeCS
Descriptor
Inglés
:
Proto-Oncogene Proteins c-akt
Descriptor
Español
:
Proteínas Proto-Oncogénicas c-akt
Descriptor
Portugués
:
Proteínas Proto-Oncogênicas c-akt
Sinónimos
Inglés
:
akt Proto-Oncogene Protein
c-akt Protein
Categoría:
D08.811.913.696.620.682.700.755
D12.776.476.565
D12.776.624.664.700.168
Definición
Inglés
:
A protein-serine-threonine kinase that is activated by
PHOSPHORYLATION
in response to
GROWTH
FACTORS or
INSULIN
. It plays a major
role
in cell
metabolism
,
growth
, and
survival
as a core component of
SIGNAL TRANSDUCTION
. Three isoforms have been described in mammalian
cells.
Nota Histórica
Inglés
:
2006(1987)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
50724
Identificador Único:
D051057
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS