Expresión de búsqueda: PAXILLIN 
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Descriptor Inglés:   Paxillin 
Descriptor Español:   Paxillin 
Descriptor Portugués:   Paxilina 
Categoría:   D12.644.360.024.309
D12.776.157.057.092
D12.776.476.024.397
D12.776.744.665
Definición Inglés:   Paxillin is a signal transducing adaptor protein for CELL MIGRATION that localizes primarily to FOCAL ADHESIONS. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK. 
Nota Histórica Inglés:   2006(1991) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   50780 
Identificador Único:   D051419 

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