Expresión de búsqueda: I-KAPPA B KINASE 
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Descriptor Inglés:   I-kappa B Kinase 
Descriptor Español:   Quinasa I-kappa B 
Descriptor Portugués:   Quinase I-kappa B 
Categoría:   D08.811.913.696.620.682.700.494
D12.644.360.376
D12.776.476.378
Definición Inglés:   A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit. 
Relacionados Inglés:   I-kappa B Proteins
 
Nota Histórica Inglés:   2006(1997) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   50718 
Identificador Único:   D051550 

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