Expresión de búsqueda: CRK-ASSOCIATED SUBSTRATE PROTEIN 
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Descriptor Inglés:   Crk-Associated Substrate Protein 
Descriptor Español:   Proteína Sustrato Asociada a CrK 
Descriptor Portugués:   Proteína Substrato Associada a Crk 
Categoría:   D12.644.360.024.295
D12.776.157.057.022
D12.776.476.024.374
D12.776.744.425
Definición Inglés:   Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It is a signal transducing adaptor protein that undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION. 
Nota Histórica Inglés:   2006(2004) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   50765 
Identificador Único:   D050719 

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