Search on: SRC-FAMILY KINASES 
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Descriptor English:   src-Family Kinases 
Descriptor Spanish:   Familia-src Quinasas 
Descriptor Portuguese:   Quinases da Família src 
Synonyms English:   src Kinases
Protein-Tyrosine Kinases, src  
Tree Number:   D08.811.913.696.620.682.725.800
Definition English:   A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes. 
See Related English:   src Homology Domains
 
History Note English:   96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   32603 
Unique Identifier:   D019061 

Occurrence in VHL:
 

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