Search on: MYC PROTO-ONCOGENE PROTEINS 
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Descriptor English:   Proto-Oncogene Proteins c-myc 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-myc 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-myc 
Synonyms English:   c-myc Proteins
L-myc Proteins
myc Proto-Oncogene Proteins
N-myc Proteins
p62(c-myc)  
Tree Number:   D12.776.260.676
D12.776.624.664.700.189
D12.776.660.765
Definition English:   Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis. 
Indexing Annotation English:   /drug eff /ultrastruct permitted; DF: note short X refs
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   29093 
Unique Identifier:   D016271 

Occurrence in VHL:
 

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