Search on: GAMMA-BUTYROBETAINE DIOXYGENASE 
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Descriptor English:   gamma-Butyrobetaine Dioxygenase 
Descriptor Spanish:   gamma-Butirobetaína Dioxigenasa 
Descriptor Portuguese:   gama-Butirobetaína Dioxigenase 
Tree Number:   D08.811.682.690.708.401
Definition English:   An enzyme that catalyzes the HYDROXYLATION of gamma-butyrobetaine to L-CARNITINE. It is the last enzyme in the biosynthetic pathway of L-CARNITINE and is dependent on alpha-ketoglutarate; IRON; ASCORBIC ACID; and OXYGEN. 
History Note English:   2006(1980); use KETOGLUTARIC ACID 1973-1974, BETAINE 1972-1979, BUTYRATES 1974-1979, & AMINOBUTYRIC ACID 1970-1974 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50661 
Unique Identifier:   D050563 

Occurrence in VHL:
 

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