Search on:
BETA 2-MICROGLOBULIN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
beta 2-Microglobulin
Descriptor
Spanish
:
Microglobulina-2 beta
Descriptor
Portuguese
:
Microglobulina-2 beta
Synonyms
English
:
Thymotaxin
Tree Number:
D12.776.124.790.223.100
D12.776.377.715.182.100
Definition
English
:
An 11-kDa protein associated with the outer membrane of many
cells
including
lymphocytes
. It is the small subunit of the MHC class I molecule.
Association
with
beta 2-microglobulin
is generally required for the transport of class I heavy chains from the
endoplasmic reticulum
to the cell surface.
Beta 2-microglobulin
is present in small amounts in
serum
, csf, and
urine
of normal people, and to a much greater degree in the
urine
and
plasma
of
patients
with tubular proteinemia, renal failure, or
kidney
transplants.
Indexing Annotation
English
:
/biosyn /physiol
/blood
permitted
History Note
English
:
91(75); was BETA 2 MICROGLOBULIN 1984-90; was see under BETA GLOBULINS 1975-83
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29233
Unique Identifier:
D001613
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS