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XAMOTEROL
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DeCS
Descriptor
English
:
Xamoterol
Descriptor
Spanish
:
Xamoterol
Descriptor
Portuguese
:
Xamoterol
Tree Number:
D02.033.100.624.972
D02.033.755.624.972
D02.092.063.624.698.855
D03.383.533.640.950
Definition
English
:
A selective beta-1-adrenergic partial agonist. Because it is a partial agonist (
DRUG PARTIAL AGONISM
) it acts like an agonist when sympathetic activity is low and as an antagonist when sympathetic activity is high. It reduces
MYOCARDIAL ISCHEMIA
and improves
ventricular function
in
patients
with mild to moderate
heart failure
. In
patients
with severe
heart failure
it has been shown to produce benefits in systolic and diastolic function.
Pharmacological Action:
Adrenergic beta-Agonists
History Note
English
:
93; was XAMOTEROL (NM) 1984-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
30458
Unique Identifier:
D017307
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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