Search on: TRYPTOPHAN OXYGENASE 
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Descriptor English:   Tryptophan Oxygenase 
Descriptor Spanish:   Triptófano Oxigenasa 
Descriptor Portuguese:   Triptofano Oxigenase 
Synonyms English:   Tryptophan Pyrrolase  
Tree Number:   D08.811.682.690.416.722
Definition English:   A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism. 
See Related English:   Tryptophan Hydroxylase
 
History Note English:   68(65) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   14768 
Unique Identifier:   D014366 

Occurrence in VHL:
 

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