Search on: TRYPTOPHAN MONOOXYGENASE 
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Descriptor English:   Tryptophan Hydroxylase 
Descriptor Spanish:   Triptófano Hidroxilasa 
Descriptor Portuguese:   Triptofano Hidroxilase 
Synonyms English:   Tryptophan Monooxygenase  
Tree Number:   D08.811.682.690.708.870
Definition English:   An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN. 
See Related English:   Tryptophan Oxygenase
 
History Note English:   78(73); was see under HYDROXYLASES 1975-77 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   14767 
Unique Identifier:   D014365 

Occurrence in VHL: 		 

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