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TESTICULAR FEMINIZATION
Descriptors Found:
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DeCS
Descriptor
English
:
Androgen-Insensitivity Syndrome
Descriptor
Spanish
:
Síndrome de Resistencia Androgénica
Descriptor
Portuguese
:
Síndrome de Resistência a Andrógenos
Synonyms
English
:
Testicular Feminization
Tree Number:
C12.706.842.316.627.109
C13.351.875.842.316.627.109
C16.131.939.842.316.627.109
C16.320.322.061
C19.391.775.316.627.500
Definition
English
:
A familial form of
PSEUDOHERMAPHRODITISM
transmitted as an X-linked recessive trait. These
patients
have a karyotype of 46,XY with end-organ resistance to androgen due to mutations in the androgen receptor (RECEPTORS, ANDROGEN) gene. Severity of the defect in receptor quantity or quality correlates with their phenotypes. In these genetic males, the phenotypic spectrum ranges from those with normal
female
external
genitalia
, through those with genital ambiguity as in Reifenstein
Syndrome
, to that of a normal
male
with
INFERTILITY.
Indexing Annotation
English
:
check the tag
MALE
History Note
English
:
2002(1968)
Allowable Qualifiers
English
:
BL
blood
CF
cerebrospinal fluid
CI
chemically induced
CL
classification
CO
complications
DI
diagnosis
DH
diet therapy
DT
drug therapy
EC
economics
EM
embryology
EN
enzymology
EP
epidemiology
EH
ethnology
ET
etiology
GE
genetics
HI
history
IM
immunology
ME
metabolism
MI
microbiology
MO
mortality
NU
nursing
PS
parasitology
PA
pathology
PP
physiopathology
PC
prevention & control
PX
psychology
RA
radiography
RI
radionuclide imaging
RT
radiotherapy
RH
rehabilitation
SU
surgery
TH
therapy
US
ultrasonography
UR
urine
VE
veterinary
VI
virology
Record Number:
14113
Unique Identifier:
D013734
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS