Search on: SMAD7 PROTEIN 
Descriptors Found: 1
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Descriptor English:   Smad7 Protein 
Descriptor Spanish:   Proteína smad7 
Descriptor Portuguese:   Proteína Smad7 
Tree Number:   D12.644.360.024.334.200.700
D12.776.157.057.170.249.700
D12.776.476.024.417.249.700
Definition English:   An inhibitory smad protein that associates with TRANSFORMING GROWTH FACTOR BETA RECEPTORS and BONE MORPHOGENETIC PROTEIN RECEPTORS. It negatively regulates SIGNAL TRANSDUCTION PATHWAYS by inhibiting PHOSPHORYLATION of RECEPTOR-REGULATED SMAD PROTEINS. 
History Note English:   2006(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50787 
Unique Identifier:   D051906 

Occurrence in VHL:
 

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