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SEROTONIN
Descriptors Found:
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DeCS
Descriptor
English
:
Serotonin
Descriptor
Spanish
:
Serotonina
Descriptor
Portuguese
:
Serotonina
Synonyms
English
:
5-HT
5-Hydroxytryptamine
Tree Number:
D02.092.211.215.801.852
D03.438.473.914.814
D23.469.050.650
Definition
English
:
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In
humans
it is found primarily in the
central nervous system
,
gastrointestinal tract
, and
blood platelets
.
Serotonin
mediates several important physiological functions including neurotransmission,
gastrointestinal motility
,
hemostasis
, and cardiovascular integrity. Multiple receptor families (RECEPTORS,
SEROTONIN
) explain the broad physiological actions and distribution of this biochemical mediator.
Indexing Annotation
English
:
/antag =
SEROTONIN ANTAGONISTS
but consider also
SEROTONIN UPTAKE INHIBITORS
Pharmacological Action:
Serotonin Agents
Entry Combination - descr/qualif
English
:
Serotonin
/
agonists
use
Serotonin Agonists
Serotonin
/
antagonists & inhibitors
use
Serotonin Antagonists
See Related
English
:
Receptors, Serotonin
Serotonin Agents
Serotonin Syndrome
History Note
English
:
HYDROXYTRYPTAMINE was see SEROTONIN 1975-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AA
analogs & derivatives
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
24311
Unique Identifier:
D012701
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS