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RECEPTORS, PLATELET-DERIVED GROWTH FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Receptors, Platelet-Derived Growth Factor
Descriptor
Spanish
:
Receptores de Factor de Crecimiento Derivado de Plaqueta
Descriptor
Portuguese
:
Receptores de Fator de Crescimento Derivado de Plaquetas
Synonyms
English
:
Platelet-Derived Growth Factor Receptors
PDGF Receptors
Receptors, PDGF
Tree Number:
D08.811.913.696.620.682.725.400.900
D12.776.543.750.060.625
D12.776.543.750.750.400.630
Definition
English
:
Specific receptors on cell
membranes
that react with
PLATELET-DERIVED GROWTH FACTOR
, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR,
PLATELET-DERIVED GROWTH FACTOR
ALPHA) and the beta PDGF receptor (RECEPTOR,
PLATELET-DERIVED GROWTH FACTOR
BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced
dimerization
or heterodimerization of PDGF receptor types.
Indexing Annotation
English
:
DF: RECEPT PDGF
See Related
English
:
Platelet-Derived Growth Factor
History Note
English
:
93; was PLATELET-DERIVED GROWTH FACTOR RECEPTOR (NM) 1982-92; PLATELET DERIVED GROWTH FACTOR RECEPTOR-KINASE was NM 1989-92
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
30547
Unique Identifier:
D017479
Occurrence in VHL
:
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