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RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Receptor, Macrophage Colony-Stimulating Factor
Descriptor
Spanish
:
Receptor de Factor Estimulante de Colonias de Macrófagos
Descriptor
Portuguese
:
Receptor de Fator Estimulador de Colônias de Macrófagos
Synonyms
English
:
c-fms Protein
fms Proto-Oncogene Protein
Proto-Oncogene Protein fms
Antigens, CD115
CD115 Antigens
CSF-1 Receptor
Receptor, CSF-1
Tree Number:
D08.811.913.696.620.682.725.400.500
D12.776.543.750.060.492
D12.776.543.750.705.852.150.150
D12.776.543.750.750.400.200.200
D12.776.624.664.700.800
D23.050.301.264.035.597
D23.101.100.110.597
Definition
English
:
A receptor for
MACROPHAGE COLONY-STIMULATING FACTOR
encoded by the c-fms proto-oncogene (
GENES
, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation,
phosphorylation
of down-stream signaling molecules and rapid
down-regulation.
Indexing Annotation
English
:
DF: RECEPT MCSF
See Related
English
:
Genes, fms
History Note
English
:
2000(1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
30890
Unique Identifier:
D016186
Occurrence in VHL
:
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DeCS
CID-10
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