Search on: PROSTAGLANDIN SYNTHASE INHIBITORS 
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Descriptor English:   Cyclooxygenase Inhibitors 
Descriptor Spanish:   Inhibidores de la Ciclooxigenasa 
Descriptor Portuguese:   Inibidores de Ciclooxigenase 
Synonyms English:   Prostaglandin Endoperoxide Synthase Inhibitors
Prostaglandin Synthase Inhibitors
Prostaglandin Synthesis Antagonists  
Tree Number:   D27.505.519.389.310
D27.505.696.663.850.014.040.500.500
D27.505.954.158.030.500
Definition English:   Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. 
Indexing Annotation English:   DF: CYCLOOXYGENASE INHIB
History Note English:   92; PROSTAGLANDIN SYNTHESIS ANTAGONISTS was see ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL 1987-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   30165 
Unique Identifier:   D016861 

Occurrence in VHL: 		 

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