Search on: PRPSC PROTEINS 
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Descriptor English:   PrPSc Proteins 
Descriptor Spanish:   Proteínas PrPSc 
Descriptor Portuguese:   Proteínas PrPSc 
Synonyms English:   Scrapie Agent
Scrapie PrP  
Tree Number:   D12.776.785.700
Definition English:   Abnormal isoform of prion proteins (PRIONS) resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES). 
Indexing Annotation English:   prion proteins; PrPSc stands for PRion Protein SCrapie; do not confuse with PRPC PROTEINS; /pathogen permitted; DF: PRPSC
History Note English:   95; SCRAPIE AGENT was see PRIONS 1992-94, was heading 1987-91, was SCRAPIE PRION 1986, was SCRAPIE VIRUS 1966-85; SCRAPIE PRP was NM 1988-94; SCRAPIE VIRUS was see PRIONS 1992-94, was see SCRAPIE AGENT 1987-91, was see SCRAPIE PRION 1986, was heading 1966-85; RIDA VIRUS was see SCRAPIE AGENT 1976-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PY pathogenicity PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   32059 
Unique Identifier:   D018620 

Occurrence in VHL:
 

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