Search on: POLYDEOXYRIBONUCLEOTIDE LIGASES 
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Descriptor English:   DNA Ligases 
Descriptor Spanish:   ADN Ligasas 
Descriptor Portuguese:   DNA Ligases 
Synonyms English:   DNA Joinases
Polydeoxyribonucleotide Ligases
Polydeoxyribonucleotide Synthetases  
Tree Number:   D08.811.074.500
D08.811.464.754.600
Definition English:   Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD). 
Indexing Annotation English:   do not confuse X ref POLYDEOXYRIBONUCLEOTIDE SYNTHETASES with X ref POLYRIBONUCLEOTIDE SYNTHETASE
History Note English:   98(77); for DNA LIGASES use POLYNUCLEOTIDE SYNTHETASES 1973-76 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   11522 
Unique Identifier:   D011088 

Occurrence in VHL:
 

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