Search on: PEPTIDE HISTIDINE-ISOLEUCINE 
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Descriptor English:   Peptide PHI 
Descriptor Spanish:   Péptido PHI 
Descriptor Portuguese:   Peptídeo PHI 
Synonyms English:   Neuropeptide PHI 27
Peptide Histidine-Isoleucine
Peptide PHM
PHI Peptide  
Tree Number:   D06.472.699.592
D12.644.400.610
D12.644.548.592
D12.776.641.650.610
Definition English:   A 27-amino acid peptide with histidine at the N-terminal and isoleucine amide at the C-terminal. The exact amino acid composition of the peptide is species dependent. The peptide is secreted in the intestine, but is found in the nervous system, many organs, and in the majority of peripheral tissues. It has a wide range of biological actions, affecting the cardiovascular, gastrointestinal, respiratory, and central nervous systems. 
Indexing Annotation English:   a neurotransmitter; X ref explains PHI; /biosyn /physiol permitted
History Note English:   87 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   19286 
Unique Identifier:   D010451 

Occurrence in VHL:
 

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