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PAXILLIN
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DeCS
Descriptor
English
:
Paxillin
Descriptor
Spanish
:
Paxillin
Descriptor
Portuguese
:
Paxilina
Tree Number:
D12.644.360.024.309
D12.776.157.057.092
D12.776.476.024.397
D12.776.744.665
Definition
English
:
Paxillin
is a signal transducing adaptor protein for CELL
MIGRATION
that localizes primarily to
FOCAL ADHESIONS
. It undergoes
PHOSPHORYLATION
in response to integrin-mediated
CELL ADHESION
, and interacts with a variety of
proteins
including
VINCULIN
; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.
History Note
English
:
2006(1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50780
Unique Identifier:
D051419
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS