Search on:
MYOSIN-LIGHT-CHAIN KINASE
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Myosin-Light-Chain Kinase
Descriptor
Spanish
:
Quinasa de Cadena Ligera de Miosina
Descriptor
Portuguese
:
Quinase de Cadeia Leve de Miosina
Synonyms
English
:
Myosin Kinase
Tree Number:
D08.811.913.696.620.682.700.125.500
D12.644.360.100.500
D12.776.476.100.500
Definition
English
:
An enzyme that phosphorylates
myosin light chains
in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires
calcium
and
CALMODULIN
. The 20-kDa
light
chain is phosphorylated more rapidly than any other acceptor, but
light
chains from other
myosins
and myosin itself can act as acceptors. The enzyme plays a central
role
in the regulation of smooth
muscle contraction.
Indexing Annotation
English
:
DF: MLCK
History Note
English
:
87
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
19253
Unique Identifier:
D009219
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS