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DeCS
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Descriptor English:
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Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
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Descriptor Spanish:
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Proteína Tirosina Quinasa p56(lck) Específica de Linfocito
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Descriptor Portuguese:
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Proteína Tirosina Quinase p56(lck) Linfócito-Específica
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Synonyms English:
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lck Kinase
p56 lck
Protein Tyrosine Kinase p56(lck)
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Tree Number:
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D08.811.913.696.620.682.725.800.315
D12.776.624.664.700.128
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Definition English:
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This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation. |
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History Note English:
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98; use LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK) (NM) 1988-97
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Allowable Qualifiers English:
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Record Number:
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33475
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Unique Identifier:
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D019860
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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