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INHIBINS
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DeCS
Descriptor
English
:
Inhibins
Descriptor
Spanish
:
Inhibinas
Descriptor
Portuguese
:
Inibinas
Tree Number:
D06.472.334.968
D06.472.699.337
D12.644.548.387
D12.776.395.439
Definition
English
:
Glycoproteins
that inhibit pituitary
FOLLICLE STIMULATING HORMONE
secretion.
Inhibins
are secreted by the
Sertoli cells
of the testes, the
granulosa cells
of the ovarian follicles, the
placenta
, and other
tissues
.
Inhibins
and
ACTIVINS
are modulators of
FOLLICLE STIMULATING HORMONE
secretions; both groups belong to the TGF-beta superfamily, as the
TRANSFORMING GROWTH FACTOR BETA
.
Inhibins
consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively
Indexing Annotation
English
:
/biosyn /physiol permitted
History Note
English
:
2002; (1983)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
7440
Unique Identifier:
D007265
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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