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IMMUNOGLOBULIN SWITCH REGION
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DeCS
Descriptor
English
:
Immunoglobulin Switch Region
Descriptor
Spanish
:
Región de Cambio de la Inmunoglobulina
Descriptor
Portuguese
:
Região de Troca de Imunoglobulinas
Synonyms
English
:
Switch Region, Immunoglobulin
Tree Number:
G05.360.340.024.340.137.430
G05.360.340.024.340.335.300.500
Definition
English
:
A site located in the
INTRONS
at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangement) occur during
IMMUNOGLOBULIN CLASS SWITCHING
. Ig switch regions are found on
genes
encoding all five classes (
IMMUNOGLOBULIN ISOTYPES
) of
IMMUNOGLOBULIN HEAVY CHAINS.
Indexing Annotation
English
:
DF: IG SWITCH REGION
See Related
English
:
Immunoglobulin Class Switching
History Note
English
:
88
Allowable Qualifiers
English
:
DE
drug effects
ES
ethics
GE
genetics
IM
immunology
IP
isolation & purification
PH
physiology
RE
radiation effects
Record Number:
24263
Unique Identifier:
D007134
Occurrence in VHL
:
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DeCS
CID-10
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