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DeCS
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Descriptor English:
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Receptor, IGF Type 1
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Descriptor Spanish:
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Receptor IGF Tipo 1
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Descriptor Portuguese:
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Receptor IGF Tipo 1
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Synonyms English:
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IGF Type 1 Receptor
IGF-I Receptor
Receptor, Insulin-Like Growth Factor I
Receptor, Insulin-Like Growth Factor Type 1
Receptor, IGF-I
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Tree Number:
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D08.811.913.696.620.682.725.400.185
D12.776.543.750.060.468
D12.776.543.750.750.400.780.400
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Definition English:
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A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The beta subunit contains an intrinsic tyrosine kinase domain. |
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Indexing Annotation English:
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DF: RECEPT IGF 1
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See Related English:
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Insulin-Like Growth Factor I
Insulin-Like Growth Factor II
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History Note English:
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2000(1993);
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Allowable Qualifiers English:
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Record Number:
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30558
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Unique Identifier:
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D017526
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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