Search on: HYALURONIDASE 
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Descriptor English:   Hyaluronoglucosaminidase 
Descriptor Spanish:   Hialuronoglucosaminidasa 
Descriptor Portuguese:   Hialuronoglucosaminidase 
Synonyms English:   Hyaluronidase  
Tree Number:   D08.811.277.450.529
D08.811.520.241.700.675
Definition English:   An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS. 
History Note English:   98(63) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   6973 
Unique Identifier:   D006821 

Occurrence in VHL:
 

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