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HUNTER CORRECTIVE FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Iduronate Sulfatase
Descriptor
Spanish
:
Iduronato Sulfatasa
Descriptor
Portuguese
:
Iduronato Sulfatase
Synonyms
English
:
Hunter Corrective Factor
Iduronatesulfate Sulfohydrolase
Sulfoiduronate Sulfatase
Tree Number:
D08.811.277.352.827.500
Definition
English
:
An enzyme that specifically cleaves the ester sulfate of
iduronic acid
. Its deficiency has been demonstrated in Hunter's
syndrome
, which is characterized by an excess of
dermatan sulfate
and heparan sulfate. EC 3.1.6.13.
Entry Combination - descr/qualif
English
:
Iduronate Sulfatase
/
deficiency
use
Mucopolysaccharidosis II
See Related
English
:
Mucopolysaccharidosis II
History Note
English
:
91(76); was see under SULFATASES 1976-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
7393
Unique Identifier:
D007066
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS