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HOMEOBOX SEQUENCE
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DeCS
Descriptor
English
:
Genes, Homeobox
Descriptor
Spanish
:
Genes Homeobox
Descriptor
Portuguese
:
Genes Homeobox
Synonyms
English
:
Genes, Homeotic
Homeobox Sequence
Homeotic Genes
Tree Number:
G05.360.340.024.340.230.500
Definition
English
:
Genes
that encode highly conserved
TRANSCRIPTION FACTORS
that
control
positional identity of
cells
(
BODY PATTERNING
) and
MORPHOGENESIS
throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these
genes
often results in homeotic transformations, in which one body structure replaces another. The
proteins
encoded by homeobox
genes
are called
HOMEODOMAIN PROTEINS.
See Related
English
:
Homeodomain Proteins
History Note
English
:
95; was GENES, HOMEO BOX 1987-94
Allowable Qualifiers
English
:
DE
drug effects
ES
ethics
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
28069
Unique Identifier:
D005801
Occurrence in VHL
:
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