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GLUCOCEREBROSIDES
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DeCS
Descriptor
English
:
Glucosylceramides
Descriptor
Spanish
:
Glucosilceramidas
Descriptor
Portuguese
:
Glucosilceramidas
Synonyms
English
:
Glucocerebrosides
Glucosyl Ceramides
Tree Number:
D02.065.313.250.490
D09.400.410.420.525.200.250.490
D10.390.470.675.200.250.490
D10.570.877.360.612.200.250.490
Definition
English
:
Cerebrosides
which contain as their polar
head
group a
glucose
moiety bound in glycosidic linkage to the hydroxyl group of
ceramides
. Their accumulation in tissue, due to a defect in
beta-glucosidase
, is the cause of Gaucher's
disease.
History Note
English
:
91(79); was see under CEREBROSIDES 1979-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
6108
Unique Identifier:
D005963
Occurrence in VHL
:
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DeCS
CID-10
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