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GEMFIBROZIL
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DeCS
Descriptor
English
:
Gemfibrozil
Descriptor
Spanish
:
Gemfibrozilo
Descriptor
Portuguese
:
Genfibrozila
Tree Number:
D02.241.081.160.225.396
D02.241.081.944.509.350
D10.251.400.895.593.350
Definition
English
:
A lipid-regulating agent that lowers elevated
serum
lipids
primarily by decreasing
serum
triglycerides
with a variable reduction in total
cholesterol
. These decreases occur primarily in the VLDL fraction and less frequently in the LDL fraction.
Gemfibrozil
increases HDL subfractions HDL2 and HDL3 as well as
apolipoproteins
A-I and A-II. Its mechanism of action has not been definitely established.
Pharmacological Action:
Antilipemic Agents
History Note
English
:
89
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23643
Unique Identifier:
D015248
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS