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FILGRASTIM
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DeCS
Descriptor
English
:
Filgrastim
Descriptor
Spanish
:
Filgrastim
Descriptor
Portuguese
:
Filgrastim
Synonyms
English
:
G-CSF Recombinant, Human Methionyl
Recombinant-Methionyl Human Granulocyte Colony-Stimulating Factor
Tree Number:
D12.644.276.374.410.240.075.350.275
D12.644.276.374.410.240.350.375.275
D12.776.395.240.075.350.275
D12.776.395.240.200.375.275
D12.776.467.374.410.240.075.350.275
D12.776.467.374.410.240.350.375.275
D12.776.828.075.350.275
D23.529.374.410.240.075.350.275
D23.529.374.410.240.350.375.275
Definition
English
:
A hematopoietic
growth
factor which promotes proliferation and maturation of neutrophil
granulocytes
. Clinically it is effective in decreasing the
incidence
of febrile
neutropenia
in
patients
with non-myeloid malignancies receiving myelosuppressive therapy or in reducing the duration of
neutropenia
and neutropenia-related clinical sequelae in
patients
with non-myeloid malignancies undergoing myeloblastive chemotherapy followed by BMT. It has also been used in AIDS
patients
with CMV
retinitis
being treated with
GANCICLOVIR
. (Gelman CR, Rumack BH & Hess AJ (eds): DRUGDEX(R) System. MICROMEDEX, Inc., Englewood,
Colorado
(Edition expires 11/30/95))
History Note
English
:
97; was FILGRASTIM (NM) 1992-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33052
Unique Identifier:
D019376
Occurrence in VHL
:
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CID-10
SciELO
LILACS
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