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ERGOLOID MESYLATES
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DeCS
Descriptor
English
:
Ergoloid Mesylates
Descriptor
Spanish
:
Mesilatos Ergoloides
Descriptor
Portuguese
:
Mesilatos Ergolóides
Synonyms
English
:
Co-Dergocrine Mesylate
Dihydroergotoxine Mesylate
Tree Number:
D03.132.327.412.250.500
D03.549.562.400.500
Definition
English
:
A mixture of the
mesylates
(
methane
sulfonates) of
DIHYDROERGOCORNINE
;
DIHYDROERGOCRISTINE
; and the alpha- and beta-isomers of
DIHYDROERGOCRYPTINE
. The substance produces a generalized peripheral
vasodilation
and a fall in arterial
pressure
and has been used to treat
symptoms
of mild to moderate impairment of mental function in the elderly.
Pharmacological Action:
Adrenergic alpha-Antagonists
Nootropic Agents
Vasodilator Agents
History Note
English
:
92; was ERGOT ALKALOIDS, HYDROGENATED 1963-91; ERGOLOID MESYLATE was see DIHYDROERGOTOXINE 1984-91; HYDERGINE was see DIHYDROERGOTOXINE 1977-91, see under ERGOT ALKALOIDS, HYDROGENATED 1963-76
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
30293
Unique Identifier:
D004877
Occurrence in VHL
:
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CID-10
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