Search on: COAGULATION FACTOR XIA 
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Descriptor English:   Factor XIa 
Descriptor Spanish:   Factor Xia 
Descriptor Portuguese:   Fator Xia 
Synonyms English:   Factor XI, Activated
Coagulation Factor XIa  
Tree Number:   D08.811.277.656.300.760.320
D08.811.277.656.959.350.320
D12.776.124.125.425.320
D23.119.425.320
Definition English:   Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium. 
Indexing Annotation English:   /defic = FACTOR XI DEFICIENCY
See Related English:   Coagulants
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   24647 
Unique Identifier:   D015945 

Occurrence in VHL: 		 

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