Search on: B-CELL ACTIVATION ANTIGEN 
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Descriptor English:   Antigens, CD80 
Descriptor Spanish:   Antígenos CD80 
Descriptor Portuguese:   Antígenos CD80 
Synonyms English:   B-Cell Activation Antigen
CD80 Antigens
B7-1 Costimulatory Molecule  
Tree Number:   D23.050.301.264.035.180
D23.101.100.110.180
Definition English:   The natural ligand for the T-cell antigen CD28; (ANTIGENS, CD28); mediating T- and B-cell adhesion. CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes. The binding of CD80 to CD28 and CTLA-4 provides a co-stimulatory signal to T-cells and leads to greatly upregulated lymphokine production. 
History Note English:   96; was B-CELL ACTIVATION ANTIGEN 1994-95; was B CELL ACTIVATION ANTIGEN B7 (NM) 1991-93; B7-1 COSTIMULATORY MOLECULE was B7-1 PROTEIN (NM) 1994-95 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PH physiology PO poisoning
RE radiation effects TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   31626 
Unique Identifier:   D018122 

Occurrence in VHL:
 

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