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ANTIGENS, KI-1
Descriptors Found:
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DeCS
Descriptor
English
:
Antigens, CD30
Descriptor
Spanish
:
Antígenos CD30
Descriptor
Portuguese
:
Antígenos CD30
Synonyms
English
:
Antigens, Ki-1
Ber-H2 Antigens
CD30 Antigens
Ki-1 Antigens
Tumor Necrosis Factor Receptor Superfamily, Member 8
Tree Number:
D12.776.543.750.705.852.760.072
D23.050.285.025
D23.050.301.264.035.130
D23.101.100.110.130
D23.101.840.055
Definition
English
:
A member of the tumor
necrosis
factor receptor superfamily that may play a
role
in the regulation of
NF-KAPPA B
and
APOPTOSIS
. They are found on activated
T-LYMPHOCYTES
;
B-LYMPHOCYTES
;
NEUTROPHILS
;
EOSINOPHILS
;
MAST CELLS
and NK
CELLS
. Overexpression of CD30 antigen in hematopoietic malignancies make the antigen clinically useful as a biological tumor marker. Signaling of the receptor occurs through its
association
with TNF RECEPTOR-ASSOCIATED FACTORS.
History Note
English
:
94; CD30 ANTIGENS was CD30 ANTIGEN (NM) 1983-93
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
31645
Unique Identifier:
D017730
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS