Search on: ANTIGENS, CD59 
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Descriptor English:   Antigens, CD59 
Descriptor Spanish:   Antígenos CD59 
Descriptor Portuguese:   Antígenos CD59 
Synonyms English:   CD59 Antigens
Homologous Restriction Factor 20
HRF20
Membrane Attack Complex Inhibition Factor
MACIF
Protectin  
Tree Number:   D12.776.395.550.035
D12.776.543.550.159
D23.050.301.264.035.159
D23.101.100.110.159
Definition English:   Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234) 
Pharmacological Action:   Complement Inactivating Agents
 
History Note English:   1996; use CD59 ANTIGEN (NM) 1989-1995, for PROTECTIN use CATIONIC PROTEIN, URATE-CALCIUM OXALATE STONE (NM) 1996-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PH physiology PO poisoning
RE radiation effects TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   32839 
Unique Identifier:   D018957 

Occurrence in VHL:
 

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