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ALU ELEMENTS
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DeCS
Descriptor
English
:
Alu Elements
Descriptor
Spanish
:
Elementos Alu
Descriptor
Portuguese
:
Elementos Alu
Synonyms
English
:
Alu Family
Alu Repetitive Sequences
Alu-Like Repetitive Sequence
Tree Number:
G02.111.570.080.708.330.800.800.050
G05.360.080.708.330.800.800.050
G05.360.340.024.425.800.800.050
Definition
English
:
The Alu sequence
family
(named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in
humans
(over a million copies). It is derived from the 7SL
RNA
component of the
SIGNAL RECOGNITION PARTICLE
and contains an
RNA polymerase III
promoter. Transposition of this element into coding and regulatory regions of
genes
is responsible for many heritable diseases.
See Related
English
:
Mutagenesis, Insertional
History Note
English
:
99; use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98
Allowable Qualifiers
English
:
DE
drug effects
ES
ethics
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
33905
Unique Identifier:
D020087
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS